Impaired Bone Growth After Ileal Augmentation Cystoplasty
作者： Jerald A. Hochstetler , Michael J. Flanigan , Karl J. Kreder
DOI: 10.1016/S0022-5347(01)64890-0
关键词: Arterial blood 、 Endocrinology 、 Bone mineral 、 Acidosis 、 Hyperchloremic acidosis 、 Internal medicine 、 Calcium 、 Hyperchloremia 、 Bone growth 、 Metabolic acidosis 、 Medicine
摘要: AbstractPurpose: We evaluated how ileal augmentation cystoplasty predisposes growing animals to hyperchloremic acidosis and abnormal skeletal development.Materials Methods: Weanling female Wistar rats weighing 35 50 gm. underwent or sham operation consisting of a similar resection closure (ileoileostomy). Both groups were stressed with 1% ammonium chloride loading. Serial bone densitometry measurements, weight blood gas studies performed in an 8-week growth period. Femur ashing mineral analysis, arterial serum determinations (calcium, magnesium phosphorus) obtained at study conclusion.Results: Augmented control had calcium, phosphorus concentrations. In augmented metabolic developed respiratory compensation decreased mean bicarbonate plus minus standard deviation compared controls (18.34 +/− 3.23 versus 21.76 2.46 mE...
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