Isolated nonapeptides presented by hla molecules, and uses thereof
作者： Catia Traversari , Pedro Romero , Den Eynde Benoit Van , Der Bruggen Pierre Van , Christoph Lurquin
DOI:
关键词: Stereochemistry 、 Hla molecules 、 Chemistry
摘要: The invention involves nonapeptides by HLA molecules such as HLA-A1. resulting complexes are identified cytolytic T cells. Such recognition may be used in diagnostics, or therapeutically.
lens.org 参考文章(20)
W E Biddison, J E Coligan, H J Zweerink, M A Bednarek, U Utz, L K Hull, K C Parker, B Cunningham, Sequence motifs important for peptide binding to the human MHC class I molecule, HLA-A2. Journal of Immunology. ,vol. 149, pp. 3580- 3587 ,(1992)
Christophe Lurquin, Pierre van der Bruggen, Etienne De Plaen, Catia Traversari, Patrick Chomez, Benoit Van den Eynde, Thierry Boon, Aline Van Pel, Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1 ,(1991)
Christophe Lurquin, Catia Traversari, Patrick Chomez, Thierry Boon, Den Eynde Benoit Van, Der Bruggen Pierre Van, Pel Aline Van, Plaen Etienne De, Tumor Rejection Antigen Precursors, Tumor Rejection Antigens and Uses Thereof ,(1992)
Christophe Lurquin, Pierre Van Der Bruggen, Etienne De Plaen, Catia Traversari, Thierry Boon-Falleur, Isolated Nonapeptide Derived from Mage-3 Gene and Presented by HLA-A1, and Uses Thereof ,(1993)
D. E. Smilek, D. C. Wraith, S. Hodgkinson, S. Dwivedy, L. Steinman, H. O. McDevitt, A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 9633- 9637 ,(1991) , 10.1073/PNAS.88.21.9633
J Ochoa-Garay, The ability of peptides to induce cytotoxic T cells in vitro does not strongly correlate with their affinity for the H-2Ld molecule: Implications for vaccine design and immunotherapy Molecular Immunology. ,vol. 34, pp. 273- 281 ,(1997) , 10.1016/S0161-5890(97)00019-9
Victor H. Engelhard, Structure of peptides associated with MHC class I molecules Current Opinion in Immunology. ,vol. 6, pp. 13- 23 ,(1994) , 10.1016/0952-7915(94)90028-0
Pierre van der Bruggen, Catia Traversari, Patrick Chomez, Christophe Lurquin, Etienne De Plaen, Benoīt Van den Eynde, Alex Knuth, Thierry Boon, None, A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma Science. ,vol. 254, pp. 1643- 1647 ,(1991) , 10.1126/SCIENCE.1840703
E. Celis, V. Tsai, C. Crimi, R. DeMars, P. A. Wentworth, R. W. Chesnut, H. M. Grey, A. Sette, H. M. Serra, Induction of anti-tumor cytotoxic T lymphocytes in normal humans using primary cultures and synthetic peptide epitopes Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 2105- 2109 ,(1994) , 10.1073/PNAS.91.6.2105
Michael L. Salgaller, Jeffrey S. Weber, Scott Koenig, John R. Yannelli, Steven A. Rosenberg, Generation of specific anti-melanoma reactivity by stimulation of human tumor-infiltrating lymphocytes with MAGE-1 synthetic peptide. Cancer Immunology, Immunotherapy. ,vol. 39, pp. 105- 116 ,(1994) , 10.1007/BF01525316