Cell patterning in the Drosophila segment: spatial regulation of the segment polarity gene patched

摘要: Intrasegmental patterning in the Drosophila embryo requires activity of segment polarity genes. The acquisition positional information by cells during embryogenesis is reflected dynamic patterns expression several these In case patched, early ubiquitous followed its repression anterior portion each parasegment; subsequently broad band splits into two narrow stripes. this study we analyse contribution other gene functions to evolution pattern; find that first step patched regulation under control engrailed whereas second both cubitus interruptusD and itself. Furthermore, products engrailed, wingless hedgehog are essential for maintaining normal pattern patched.