A decade with agammaglobulinemia.

摘要: Summary This progress report is presented a decade after recognition of patient with agammaglobulinemia. It includes brief description and follow-up the first recognized patient, summary significant advances in elucidation agammaglobulinemia as disease entity, some predictions on type which may be made this field. Although child reported has never been able to synthesize gamma globulin, adequate treatment globulin permitted normal growth development without complications other cases. Acquired secondary forms thedisease can distinguished from congenital form. postulated that acquired form itself result misdirected immunologic reaction. The paradox rheumatoid syndrome occurring agammaglobulinemic could synthesis an abnormal protein by dysfunctioning cells. probable multietiological factors producing suggest diagnosis at future date will complete only if designated its basic defect. great importance impetus it given study mechanisms man, furtherance accomplishing organ transplants, attempt find key control many diseases caused metabolism.