Imaging spectrum in disseminated histoplasmosis: case report and brief review.

作者: SB Grover , N Midha , M Gupta , U Sharma , VH Talib

DOI: 10.1111/J.1440-1673.2005.01369.X

关键词: Acquired immunodeficiency syndrome (AIDS)TuberculosisDiabetes mellitusPathologyMediastinal lymphadenopathyLungHistoplasmosisMedicineHypoadrenalismIncidence (epidemiology)

摘要: Summary The clinical manifestations of chronic disseminated histoplasmosis are non-specific and resemble those other infections malignancies. We report the radiographic, sonographic contrast-enhanced CT appearances in an adult male with non-insulin dependent diabetes mellitus, who was HIV negative presented weight loss pyrexia. Imaging studies simulated tuberculosis mediastinal lymphadenopathy, bilateral fibrotic lung lesions, hepatomegaly hypoattenuating adrenal enlargement, without or laboratory evidence hypoadrenalism. Computed tomography-guided fine-needle aspiration biopsy glands revealed Histoplasma capsulatum. our experience to increase awareness imaging spectrum its similarity as, increasing incidence AIDS, chances these likely increase. Moreover, this entity is important because it known that untreated fatal.

参考文章(9)
J. Lee, P.H. Jones, J.E. Trowell, W.P. Whitear, P.F. Williams, Hypoadrenal crisis caused by disseminated histoplasmosis Journal of Infection. ,vol. 27, pp. 181- 183 ,(1993) , 10.1016/0163-4453(93)94836-Z
D R Radin, Disseminated histoplasmosis: abdominal CT findings in 16 patients. American Journal of Roentgenology. ,vol. 157, pp. 955- 958 ,(1991) , 10.2214/AJR.157.5.1927816
Sanjeev Deodhare, Michelle Sapp, Adrenal histoplasmosis: Diagnosis by fine-needle aspiration biopsy Diagnostic Cytopathology. ,vol. 17, pp. 42- 44 ,(1997) , 10.1002/(SICI)1097-0339(199707)17:1<42::AID-DC8>3.0.CO;2-R
R.P. Goswami, N. Pramanik, D. Banerjee, M.M. Raza, S.K. Guha, P.K. Maiti, Histoplasmosis in eastern India: the tip of the iceberg? Transactions of The Royal Society of Tropical Medicine and Hygiene. ,vol. 93, pp. 540- 542 ,(1999) , 10.1016/S0035-9203(99)90374-7
W R Gibb, A D Ramsay, N I McNeil, O M Wrong, Bilateral adrenal masses. BMJ. ,vol. 291, pp. 203- 204 ,(1985) , 10.1136/BMJ.291.6489.203
M. A. Swartz, R. H. Scofield, W. D. Dickey, J. L. Kirk, D. A. Wilson, J. V. Pitha, H. G. Muchmore, Unilateral Adrenal Enlargement Due to Histoplasma capsulatum Clinical Infectious Diseases. ,vol. 23, pp. 813- 815 ,(1996) , 10.1093/CLINIDS/23.4.813
Alla M. Rozenblit, Andrew Kim, Joseph Tuvia, Bruce M. Wenig, Adrenal Histoplasmosis Manifested as Addison’s Disease: Unusual CT Features with Magnetic Resonance Imaging Correlation Clinical Radiology. ,vol. 56, pp. 682- 684 ,(2001) , 10.1053/CRAD.2000.0713
Errol Levine, CT evaluation of active adrenal histoplasmosis. Urologic Radiology. ,vol. 13, pp. 103- 106 ,(1991) , 10.1007/BF02924600
A Kawashima, C M Sandler, E K Fishman, C Charnsangavej, K Yasumori, H Honda, R D Ernst, N Takahashi, B K Raval, K Masuda, S M Goldman, Spectrum of CT findings in nonmalignant disease of the adrenal gland. Radiographics. ,vol. 18, pp. 393- 412 ,(1998) , 10.1148/RADIOGRAPHICS.18.2.9536486