Psychological and educational interventions for preventing depression in children and adolescents

摘要: Background Depression is common in young people, has a marked negative impact and associated with self-harm suicide. Preventing its onset would be an important advance public health.   Objectives To determine whether psychological or educational interventions, both, are effective preventing the of depressive disorder children adolescents. Search methods The Cochrane Depression, Anxiety Neurosis Review Group's trials registers (CCDANCTR) were searched at editorial base July 2010. Update searches MEDLINE, EMBASE, PsycINFO ERIC conducted by authors September 2009. Conference abstracts, reference lists included studies reviews experts field contacted. Selection criteria Randomised controlled prevention programmes, compared placebo, any comparison intervention, no intervention for people aged 5 to 19 years-old, who did not currently meet diagnostic criteria depression below clinical range on standardised, validated, reliable rating scales depression, included. Data collection analysis Two independently assessed inclusion rated their quality. Sample sizes adjusted take account cluster designs multiple comparisons. We contacted study additional information where needed.  Main results Fifty-three including 14,406 participants analysis. There only six clear allocation concealment, assessors mostly blind blinding was unclear so that overall risk bias moderately high. Sixteen 3240 reported outcomes diagnosis. The having post-intervention reduced immediately (15 studies; 3115 difference (RD) -0.09; 95% confidence interval (CI) -0.14 -0.05; P<0.0003), three nine months (14 1842 participants; RD -0.11; CI -0.16 -0.06) 12 (10 1750 -0.06; -0.11 -0.01). evidence continued efficacy 24 (eight 2084 participant; -0.01; -0.04 0.03) but limited 36 (two 464 -0.10; -0.19 -0.02). significant heterogeneity all these findings. few placebo attention controls. Authors' conclusions There some from this review targeted universal programmes may prevent disorders intervention. However, concealment most studies, there findings. The persistence findings suggests real effect.