The Carbonic Anhydrase as a Paragon: Theoretical and Experimental Investigation of Biomimetic Zinc-Catalyzed Activation of Cumulenes

摘要: Biomimetics as an interdisciplinary concept involves learning from and imitating of nature using appropriate models. The mimicry biological models does not only consist the construction engineering systems modern technology, furthermore, it is able to be a guide for designing architecturing in complete range natural sciences. In particular, actual development novel uncommon chemical reactions aimed apply high optimized, biochemical processes laboratory industrially usable syntheses. Especially enzymes stand visual focus highly efficient almost extreme specialized catalysts, has had long time develop optimize wide diversity life. Nearly every organism owns different tissues, motion types, sensoring functions surviving instincts basis all these properties are catalyzed reactions. Organisms have synthesize huge biopolymers growth, but also provide small molecules signal transduction, energy transfers or regulation processes. Therefore, obvious that study those gives insights important processes, suggests new pathways use synthesis other related appliances. possibilities biomimetics chemistry outlined on enzyme carbonic anhydrase. As this one most catalysts originated by nature, investigation such catalytical active protein enriches knowledge mechanisms their mode action, detailed information about center inside enzyme. way, can fathom out factors growth well diseases glitches. chapter we describe enzymatic metal mediated reaction cumulene system carbon dioxide with water its extention bio-analogue activation further isoelectronic cumulenes (carbonyl sulfide, isothiocyanate allene).