Macromolecular crowding converts the human recombinant PrPC to the soluble neurotoxic beta-oligomers

作者: Liqin Huang , Rui Jin , Jiarui Li , Kan Luo , Tao Huang

DOI: 10.1096/FJ.09-150987

关键词: Proteinase KProtein structureBiochemistryGene isoformThioflavinMacromolecular crowdingIntracellularRecombinant DNACircular dichroismChemistry

摘要: … Such a condition is referred as macromolecular crowding. Crowding can be mimicked in … In the present study, we found that macromolecular crowding may be a potential intracellular …

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