Biliary Cryptosporidiosis in HIV-Infected People after the Waterborne Outbreak of Cryptosporidiosis in Milwaukee

作者: Nimish B. Vakil , Steven M. Schwartz , Brian P. Buggy , Charles F. Brummitt , Mazen Kherellah

DOI: 10.1056/NEJM199601043340104

关键词: OutbreakSurvival analysisAIDS-Related Opportunistic InfectionsRetrospective cohort studyViral diseaseMedicineDiarrheaInternal medicineImmunologyCryptosporidiumEpidemiology

摘要: Background In March 1993, the municipal water supply in Milwaukee became contaminated with cryptosporidium and a widespread outbreak of cryptosporidiosis occurred. Methods We retrospectively studied relations among clinical presentation, CD4 count, survival group 82 patients infected human immunodeficiency virus (HIV) whom developed during outbreak. Infection was documented by finding stool. Results There sharp increase number HIV-infected after period contamination. Four 24 biliary symptoms (17 percent) 30 58 without (52 were alive one year (P = 0.003). Twenty-one had counts <50 per cubic millimeter, as compared 36 57 (88 percent vs. 63 percent, P 0.03). The count not available for patient latte...

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