Secondary Sclerosing Cholangitis

摘要: Sclerosing cholangitis is a description for pattern of biliary inflammation and scarring, typically identified by imaging or histopathologic evaluation liver tissue. It an umbrella term variety processes that lead to fibrosing cholangiopathy. Gaining insights from known secondary aetiologies important in attempting understand the mechanisms behind primary disease, which there remains no present treatment. Notable include ischemia, infection, autoimmunity, infiltration toxic injury particular. Patient presentation sclerosing can be varied, but careful history taking critical review serologic studies usually identifies aetiology. Particular attention identifying should made when patients atypical ways, disease course not as expected. This includes with overt absent colitis, family those systemic manifestations might suggest IgG4-associated disease. chapter focuses on cholangitis, expanding mechanistic particular regards this unusual injury.