In vitro evaluation of mechanical properties of platelet-rich fibrin membrane and scanning electron microscopic examination of its surface characteristics.

摘要: Background: The aim of this study was to evaluate the mechanical properties platelet-rich fibrin (PRF) membrane and compare these with that commercially available collagen membranes used for guided tissue regeneration (GTR) procedures. Scanning electron microscopic (SEM) examination PRF also performed determine cell distribution pattern within different regions membrane. Materials Methods: Modulus elasticity hardness (i) (ii) bovine (iii) fish were assessed by performing surface indentation test using T1 950 Triboindenter. in vitro degradation tests conducted placing equal sizes (10 mm Χ 5 mm) ml pH 7.4 phosphate buffer solution on a shaker set at 40 rpm 1-week. profiles expressed as accumulated weight losses SEM evaluation done under both low high magnification. Results: Young's found be 0.35 GPa membrane, 2.74 1.92 collagen. 10.67 MPa 110.7 90.5 degraded about 36% initial after 1-week shaking test. Fish 8% weight, 3% weight. Dense clusters platelets formed due extensive aggregation, few leukocytes observed buffy coat area. Conclusions: preliminary findings from assessment showed it lacking several desired when compared membranes. Lack rigidity faster may limit its application GTR