Impact of adult growth hormone deficiency on metabolic profile and cardiovascular risk [Review].
作者： Lara Giovannini , Giacomo Tirabassi , Giovanna Muscogiuri , Carolina Di Somma , Annamaria Colao
DOI: 10.1507/ENDOCRJ.EJ15-0337
关键词: Insulin resistance 、 Oxidative stress 、 Endocrinology 、 Carbohydrate metabolism 、 Proinflammatory cytokine 、 Obesity 、 Internal medicine 、 Inflammation 、 Quality of life 、 Physiology 、 Endothelial dysfunction 、 Biology
摘要: Adult growth hormone deficiency (GHD) is a well defined clinical condition, which characterized by abnormal body composition, impaired physical activity and decreased quality of life. In addition, in recent years, growing interest has been shown towards cardiovascular risks adult patients affected GHD. this regard, GHD widely known to be associated with increased mortality, likely due the increase risk factors, such as central obesity, lipid glucose profiles other less-known inflammatory cytokines, endothelial dysfunction oxidative stress. However, very few papers have recently discussed topic. review, aim clarify issue discussing evidence regarding effects on metabolic profiles.
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