Advances in monitoring and toxicity assessment of brevetoxins in molluscan shellfish.

作者: Steven M. Plakas , Robert W. Dickey

DOI: 10.1016/J.TOXICON.2009.11.007

关键词: MicrobiologyMarine toxinNeurotoxic shellfish poisoningAquatic organismsBrevetoxinShellfishEnvironmental chemistryShellfish poisoningClinical diagnosisToxicityBiology

摘要: Herein, we describe advancements in monitoring of brevetoxins molluscan shellfish, with respect to exposure management and control neurotoxic shellfish poisoning (NSP). Current knowledge the fate toxic potency brevetoxin metabolites, is presented. We review rapid assays for measuring composite brevetoxins, methodology constituent contaminated shellfish. The applicability vitro methods estimating burden toxicity assessed. Specific measurable biomarkers human intoxication, are described. Their utility regulatory clinical diagnosis NSP evaluated.

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