作者: Steven M. Plakas , Robert W. Dickey
DOI: 10.1016/J.TOXICON.2009.11.007
关键词: Microbiology 、 Marine toxin 、 Neurotoxic shellfish poisoning 、 Aquatic organisms 、 Brevetoxin 、 Shellfish 、 Environmental chemistry 、 Shellfish poisoning 、 Clinical diagnosis 、 Toxicity 、 Biology
摘要: Herein, we describe advancements in monitoring of brevetoxins molluscan shellfish, with respect to exposure management and control neurotoxic shellfish poisoning (NSP). Current knowledge the fate toxic potency brevetoxin metabolites, is presented. We review rapid assays for measuring composite brevetoxins, methodology constituent contaminated shellfish. The applicability vitro methods estimating burden toxicity assessed. Specific measurable biomarkers human intoxication, are described. Their utility regulatory clinical diagnosis NSP evaluated.