Structure and Virus-Associated Oncogenes of Avian Sarcoma and Leukemia Viruses

摘要: The aim of the review presented here is to give a brief overview avian retroviruses, disease they cause and genes gene products that are thought be associated with transformation target cells, in order provide common basis knowledge for readers this monograph. Retroviruses interest first as pathogens number vertebrate species, second major tool experimental oncologists. speed reliability which these small viruses tumors animals, analogous changes tissue culture, suggested early on an understanding retroviral functions would basic information primary mechanisms cancer causation. This belief being justified by results recent years. A genes, originally described retroviruses subsequently uninfected have been found variety non-avian origin. However, many respects virus remains most productive avenue investigation cogene function.