Loratadine. A review of recent findings in pharmacology, pharmacokinetics, efficacy, and safety, with a look at its use in combination with pseudoephedrine.

摘要: Antihistamines are considered first-line therapy for the relief of symptoms from allergic rhinitis and chronic urticaria. The newer, second-generation, nonsedating antihistamines reduce central nervous system anticholinergic side effects commonly found with previous drugs. availability H1-receptor antagonists that produce therapeutic without causing unwanted CNS fulfills an important practical need, since these drugs clearly preferable in patients who drive or operate heavy machinery, involved activities requiring full alertness. Physicians alike pleased efficacy safety second-generation bring to treatment allergy symptoms. Loratadine is especially effective antagonist comparable many other antihistamines. may be particularly advantageous because its low dose convenience once-daily dosing. A more subtle advantage, loratadine's antiallergic properties, warrant use specific situations as future research clarifies nature inflammatory response mechanisms action have this regard.