Selective grignard-type carbonyl addition of alkenyl halides mediated by chromium(II) chloride
作者： Kazuhiko Takai , Keizo Kimura , Tooru Kuroda , Tamejiro Hiyama , Hitosi Nozaki
DOI: 10.1016/S0040-4039(00)88417-8
关键词: Iodide 、 Aldehyde 、 Bromide 、 Chemistry 、 Grignard reaction 、 Medicinal chemistry 、 Moiety 、 Ketone 、 Organic chemistry 、 Chromium(II) chloride 、 Aryl
摘要: Abstract Alkenyl (or aryl) iodide bromide) is readily reduced with CrCl2 N,N-dimethylformamide at 25°C to gice the corresponding organochromium species which adds selectively an aldehyde moiety without affecting coexisting ketone or cyano group of substrate.
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