Evidence that Additions of Grignard Reagents to Aliphatic Aldehydes Do Not Involve Single-Electron-Transfer Processes
作者： Douglas A. L. Otte , K. A. Woerpel
DOI: 10.1021/ACS.ORGLETT.5B01893
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摘要: Addition of allylmagnesium reagents to an aliphatic aldehyde bearing a radical clock gave only addition products and no evidence ring-opened that would suggest single-electron-transfer reactions. The analogous Barbier reaction also did not provide for mechanism in the step. Other Grignard (methyl-, vinyl-, t-Bu-, triphenylmethylmagnesium halides) do appear add alkyl by mechanism.
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