Argyrophil cells in early gastric carcinoma: an immunohistochemical and ultrastructural study.

摘要: Eighteen argyrophil cell carcinomas in 101 early gastric were examined histologically, ultrastructurally, and immunohistochemically for polypeptides, carcinoembryonic antigen (CEA), lysozyme, human chorionic gonadotrophin (hCG). Seven of these 18 tumors had gastrin, two seven also contained somatostatin. In all CEA demonstrated. lysozyme five gastrin; hCG present four CEA, mucin, simultaneously. Argentaffin cells found tumors. Of the above containing three argentaffin cells. Ultrastructurally, several types secretory granules noted tumor resembling D1-or P nine Macroscopically, many showed IIc or IIc+III type. Histologically, consisted six well differentiated adenocarcinomas 12 poorly including signet-ring carcinoma. These frequently developed stomach young females. view our previous investigations, it was suggested that IIc-type carcinoma histologically showing adenocarcinoma may be related to scirrhous stomach.