Effects of the herbicide isopropyl-N-phenyl carbamate on microtubules and MTOCs in lines of Nicotiana sylvestris resistant and sensitive to its action.
作者： A YEMETS , O STELMAKH , Y BLUME
DOI: 10.1016/J.CELLBI.2008.01.012
关键词: Botany 、 Microtubule 、 Spindle pole body 、 Microtubule organizing center 、 Tubulin 、 Biophysics 、 Multipolar spindles 、 Plant cell 、 Mitosis 、 Biology 、 Nicotiana sylvestris
摘要: To clarify the mechanism of isopropyl-N-phenyl carbamate (IPC) action on higher plant cells sensitivity microtubules (cortical network and mitotic arrays) microtubule organizing centers to IPC treatment (30 μM) in IPC-resistant sensitive Nicotiana sylvestris lines was studied. It clearly demonstrated that does not depolymerize MTs but causes MTOC damage cells, which results fragmentation, splitting spindle poles abnormal division formation. also found IPC-resistance mutant N. line correlates with tubulin resistance possibly one proteins involved composition.
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