Systematic Review

作者: Alfredo J. Lucendo , Beatriz Serrano-Montalbán , Ángel Arias , Olga Redondo , José M. Tenias

DOI: 10.1097/MPG.0000000000000766

关键词: Objective evaluationEosinophilic gastroenteritisInternal medicineMedicineDietary treatmentPathologySymptom reliefMEDLINEPublication biasDisease remissionColitisPediatrics, Perinatology, and Child HealthGastroenterology

摘要: OBJECTIVES Various dietary interventions have been used to treat patients with eosinophilic gastroenteritis (EGE). Concrete evidence as the effectiveness of such treatments in inducing disease remission is, however, lacking. The aim study was systematically review efficacy therapies EGE remission. METHODS We performed a systematic search for MEDLINE, EMBASE, and SCOPUS libraries studies investigating (in both histological symptomatic remission) children adults colitis. RESULTS yielded 490 references; 30 were included review, most these references being "low-quality" individual cases or short case series. No significant publication bias found. Elemental diets linked 75.8% clinical improvement, but few underwent evaluation. Allergy-testing results scarcely EGE. Empiric elimination allergy-associated foods commonly option. variable terms symptom relief, accompanied by confirmation. Clinical methodological heterogeneity hindered performance quantitative summaries CONCLUSIONS Symptomatic improvements reported treatment available literature are questionable because lack objective evaluation changes very limited assessment Because relative well-designed, high-quality studies, unequivocal use colitis cannot be supported. Further research should undertaken.

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