Vaccine for the prevention of breast cancer recurrence

作者: George Peoples , Sathibalan Ponniah

DOI:

关键词: OncologyInternal medicineBreast cancerBooster doseT cell immunityNeu oncogeneBreast cancer recurrenceMedicineAdjuvantCytotoxic T cellImmunologyImmunity

摘要: Provided are methods to induce and maintain a protective cytotoxic T-lymphocyte response peptide of the HER/neu oncogene, GP2, with effect inducing maintaining or therapeutic immunity against breast cancer in patient clinical remission, including patients having low intermediate levels HER2/neu expression. The comprise administering an effective amount vaccine composition comprising pharmaceutically acceptable carrier, adjuvant such as GM-CSF, GP2 peptide. may further periodic booster dose needed due declining GP2-specific T cell immunity. Also provided compositions for use methods.

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