Epidemiologic typing of nosocomial microorganisms
作者： Robert C. Aber , Donald C. Mackel
DOI: 10.1016/0002-9343(81)90552-0
关键词: Medicine 、 Microorganism 、 Bacteriophage 、 Phage typing 、 Plasmid 、 Restriction enzyme 、 Antiinfective agent 、 Microbiology 、 Typing 、 Serotype 、 General Medicine
摘要: Abstract Hospital epidemiologists often rely upon "typing" of microorganisms to help determine their genetic relatedness. Most general clinical microbiology laboratories can biologic profiles (biotypes) and antimicrobial susceptibility patterns (antibiograms) bacteria commonly isolated from specimens; occasionally serologic typing (serotype) is also performed. Special interest provide typing, bacteriophage (phage typing), bacteriocin production patterns, plasmid analyses chromosomal DNA for a variety bacteria, mycobacteria fungi nosocomial interest. Such restriction enzyme other special studies viruses related microorganisms. A useful effective system should be (1) standardized, (2) reproducible, (3) sensitive, (4) stable, (5) available, (6) inexpensive, (7) applicable wide range microorganisms, (8) field tested in conjunction with epidemiologic investigation. Results reported standard manner some discussion the implications limitations results. We suggest that registry methods established facilitate application available appropriate investigations.
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