Lung Cancer in Patients with Chronic Obstructive Pulmonary Disease
作者： Juan P. de Torres , Jose M. Marín , Ciro Casanova , Claudia Cote , Santiago Carrizo
DOI: 10.1164/RCCM.201103-0430OC
关键词: Pulmonary function testing 、 Prospective cohort study 、 Carcinoma 、 COPD 、 Incidence (epidemiology) 、 Lung cancer 、 Cohort 、 Medicine 、 Internal medicine 、 Oncology 、 Airway obstruction
摘要: Rationale: Little is known about the clinical factors associated with development of lung cancer in patients chronic obstructive pulmonary disease (COPD), although airway obstruction and emphysema have been identified as possible risk factors.Objectives: To explore incidence, histologic type, diagnosis a cohort outpatients COPD attending clinic.Methods: A 2,507 without initial or radiologic evidence was followed median 60 months (30–90). At baseline, anthropometrics, smoking history, function, body composition were recorded. Time to type then registered. Cox analysis used diagnosis.Measurements Main Results: total 215 developed (incidence density 16.7 cases per 1,000 person-years). The most frequent squamou...
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