SPECTRAL STUDIES OF PRODUCTS OF REACTION BETWEEN PHOSPHORYLACETALDEHYDE THIOSEMICARBAZONES AND BROMOACETAL

摘要: We have obtained thiazoline hydrobromides by reacting unsubstituted thiosemicarbazones of phosphoryl-acetaldehydes with bromoacetal. These the structure azine phosphorylacetaldehyde and 1,3-thiazoln-2-one in crystal phase. Their dissolution is accompanied thiazoline-thiazole tautomeric conversion to hydrobromide phosphorylacetaladehyde thiazolylhydrazone. Reaction 2-methyl-substituted thiosemicarbazone bromoacetal leaas N-methyl-N-2-(1,3-thiazolyl)hydrazone, thiazole heterocycle this compound also retained when it dissolved, due impossibility conversions structural features. In all cases, salt formation occurs at endocyclic nitrogen atom. The salt-like compounds free bases does not lead a change heterocycle.