Role of CT in Differentiating Malignant Focal Splenic Lesions

摘要: Objective The purpose of this study was to asses the CT findings and clinical features differentiating malignant from benign focal splenic lesions. Materials Methods Among 673 patients with splenectomy, we included 114 pathologically confirmed lesions (malignant = 66, 48). Two radiologists retrospectively assessed including: size, number, solid component, margin, wall, calcification, contrast-enhancement, lymph node (LN) enlargement possible malignancy. We including age, sex, underlying malignancy, fever, leukocytosis. Multivariate logistic regression analysis performed identify significant predictors lesion. used receiver operating curve for determination diagnostic performance. Results Common include enhanced, mainly solid, ill-defined absence splenomegaly, LN enlargement, presence malignancy (p < 0.05). them, (odds ratio [OR], 39.098, p 0.007), (OR, 6.326, 0.005), 8.615, 0.001) were mean size (5.8 ± 3.3 cm) larger than that (4.0 3.4 cm). Diagnostic performance by two reviewers using characteristic differentiation 0.856 0.893, respectively. Conclusion Solid nature mass on images, are