Cyclodextrin-Based Porous Nanocapsules

作者: Youqing Wang , Baohang Han

DOI: 10.1002/CJOC.201300270

关键词: MoleculeNanocapsulesNanotechnologyPolymerizationMiniemulsionDrug deliveryPorosityHomogeneousChemistryCyclodextrinGeneral chemistry

摘要: Cyclodextrins (CDs) are regarded as one kind of the most important and promising macrocyclic oligosaccharides, which contain hydrophobic internal cavities capable hosting various guest molecules. CDs water-soluble, non-toxic, commercially available well low-cost. Because these favorable characteristics, cyclodextrin chemistry has created a great number interesting works covering different fields, in particular CD-based porous nanocapsules (CDPNCs). Chemical cross-linking is an way developed to prepare CDPNCs. CDPNCs can be obtained using cross-linkers preparation methods, such homogeneous method, miniemulsion polymerization, emulsion-solvent evaporation method. cross-linking, three-dimensional network built forms structure with CDs. Attributed structure, exhibit excellent performances encapsulation targeted molecules realization controllable release, indicating prospect applications drug delivery systems environment protection.

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