Secretion and Metabolism of Steroids in Subprimate Mammals During Pregnancy

摘要: The establishment and maintenance of pregnancy in the majority viviparous mammals evolved through utilization steroids, namely progesterone, to regulate maternal system during gestation (1). Formation corpus luteum (CL) progesterone release following ovulation Graafian follicle clearly have an established function regulating myometrial contractility, uterine receptivity conceptus, endometrial secretion for growth development conceptus. Placental steroidogenesis steroid metabolism also varying degrees necessity within diverse mammalian species. Species vary not only sophistication placental steroidogenic capabilities, but stage at which qualitative quantitative changes are activated. For example, bovine ovine species can maintain ovariectomy later stages contrast pig goat, cannot, equine, corpora lutea undergo a normal process luteolysis midgestation become totally reliant on contributions progesterone. increased capacity synthesize by placenta bovine, ovine, equine adaptations fetal-placental unit assert local progestational control last trimester pregnancy. play vital role fetal survival regulation nutrient flow, be it directing synthesis (2–6), modulating blood flow utero-placental (7,8), or providing one possible avenue immunological immune prevent rejection allograft (9–12). intent present chapter is provide insight into our current knowledge concerning various subprimate