Molecular imaging with CARS micro-spectroscopy.
作者： Marcus Cicerone
DOI: 10.1016/J.CBPA.2016.05.010
关键词: Chemistry 、 Broadband 、 Molecular imaging 、 Micro spectroscopy 、 Fingerprint (computing) 、 Raman scattering 、 Raman spectroscopy 、 Modality (human–computer interaction) 、 Nanotechnology 、 Remote sensing 、 Pixel
摘要: After more than a decade of instrument and method development, broadband coherent anti-Stokes Raman scattering (CARS) micro-spectroscopy is beginning to live up its potential as label-free imaging modality that can rapidly generate high resolution images with full vibrational spectra at each image pixel. Presently these instruments are able obtain quantitative, spatially resolved information on lipids from the CH stretch region spectrum, some designs facilitate acquisition quality fingerprint spectra, containing host molecular species including structural proteins, nucleotides, metabolites. While most existing research projects themselves, it appears relevant technologies maturing so commercially available may not be too far in future, making this remarkable widely available.
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