The origin of the frequency selectivity in VOR motor learning revealed by a realistic cerebellar spiking neuron network model

摘要: The vestibuloocular reflex (VOR) counter rotates the eyes in orbit during head rotation to obtain stable vision. It has been a popular model system investigate cerebellar motor learning. gain of VOR (eye velocity / velocity) can be modified by giving visual stimuli in- or out-of-phase with vestibular subject [1]. shown that learning exhibits frequency selectivity. Namely, greatest change occurs at used for training, and less changes frequencies further from training [2,3]. Existence multiple channels process different bands proposed explain this phenomenon, although corresponding neuronal circuitries have not identified anatomically physiologically. In support VOR, it demonstrated gains changed differentially 2 simultaneously (ex. decrease 0.05Hz increase 2.5Hz) squirrel monkeys [4] goldfish [5].