Computer Simulation of Vestibuloocular Reflex Motor Learning Using a Realistic Cerebellar Cortical Neuronal Network Model

摘要: The vestibuloocular reflex (VOR) is under adaptive control to stabilize our vision during head movements. It has been suggested that the acute VOR motor learning requires long-term depression (LTD) and potentiation (LTP) at parallel fiber --- Purkinje cell synapses in cerebellar flocculus. We simulated basing upon LTD LTP using a realistic cortical neuronal network model. In this model, were induced by spike timing dependent plasticity rule, which considers of occurrence climbing fibers innervating same cell. model was successful reproduce changes eye movement simple firing modulation dark after low high gain learning.