Current Status of the Development of BioglassR Ossicular Replacement Implants

摘要: The unique bonding characteristics of UF45S5 Bioglass®1, 2, 3 (discussed in another chapter this book, reference 4) prompted these investigators to pursue a series experiments evaluate Bioglass® middle ear setting. incus replacement model was chosen and developed since it replicated many the requirements clinical ossicular reconstruction. Results 60 mice for periods 21 300 days indicated that rods remained position on malleus or stapes both 85% were stable blast nitrogen gas and/or pick manipulation 85%. Histologic study revealed entirely covered by very thin capsule, places only 1 2 collagen fibers thick, normal appearing mucosa without any sign inflammation5.