Monofunctional platinum(II) compounds and nucleolar stress: is phenanthriplatin unique?
作者： Christine E. McDevitt , Matthew V. Yglesias , Austin M. Mroz , Emily C. Sutton , Min Chieh Yang
DOI: 10.1007/S00775-019-01707-9
关键词: Chemistry 、 Structure–activity relationship 、 Cytotoxicity 、 DNA damage 、 Platinum 、 Nucleophosmin 、 Phenanthriplatin 、 Biophysics 、 Cisplatin 、 Nucleolus
摘要: … mode of platinum, we next tested pyriplatin (4). Similar to picoplatin, pyriplatin contains a single aromatic ring. However, unlike picoplatin, pyriplatin has more possible orientations of the …
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