作者: Wen-Yueh Cheng , Hsiao-Chi Wang , Ming-Tsan Liu , Ho-Sheng Wu
DOI: 10.1002/JMV.23451
关键词: Outbreak 、 Notifiable disease 、 High coverage 、 Genotype 、 Virus transmission 、 Transmission (medicine) 、 Rubella 、 Virus 、 Virology 、 Biology 、 Infectious Diseases
摘要: Rubella has been listed as a mandatory notifiable disease in Taiwan since 1988. Because of high coverage rates with an effective vaccine, rubella cases have decreased dramatically 1994. However, outbreaks still occur due to imported transmission. Five large clusters were detected from 2007 2011. In 2007, one cluster was caused by genotype 1E viruses that Vietnam, whereas another 2B and untraceable. 2008, two different lineages Malaysia. 2009, associated Vietnam. The 124 confirmed 2005 2011 characterized, the data revealed these distributed following four genotypes: (n = 56), 1h (n = 1), 1j (n = 4), (n = 63). Of viruses, 93 (75%) cases, 43 56 China, Malaysia, Indonesia. One virus Belarus, three Philippines. 63 46 Thailand, Germany, South Africa. Molecular surveillance allows for differentiation circulating can be used investigate transmission pathways, which are important identify interruption endemic J. Med. Virol. 85:745–753, 2013. © 2013 Wiley Periodicals, Inc.