作者: S. E. Reef , P. Strebel , A. Dabbagh , M. Gacic-Dobo , S. Cochi
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摘要: Rubella, usually a mild rash illness in children and adults, can cause serious consequences when pregnant woman is infected, particularly early pregnancy. These include miscarriage, fetal death or an infant born with birth defects (i.e., congenital rubella syndrome (CRS)). The primary purpose for vaccination the prevention of infection including CRS. Since 1969, several virus vaccines have been licensed use; however, until 1990s, use rubella-containing vaccine (RCV) was limited primarily to developed countries. In 1996, it estimated that 110,000 infants CRS were annually developing 2000, first World Health Organization position paper published guide introduction RCV national childhood immunization schedules. From 1996 2009, number countries introduced into their routine programs increased by 57% from 83 130 2009. addition, three six WHO regions established control goals: Region Americas Europe elimination 2010 2015, respectively, Western Pacific Region-accelerated 2015. Also, during this time period, cases reported decreased 670,894 2000 121,344 Rubella be accelerated integrating current global measles mortality reduction regional activities.