Functional Interactions Between MMPs and TGF-β in Normal and Tumor Tissue
作者： Christina H. Stuelten , Anita B. Roberts , William G. Stetler-Stevenson
DOI: 10.1007/978-1-59745-292-2_17
关键词: Tumor tissue 、 Tissue maintenance 、 Wound healing 、 Cell signaling 、 Cancer research 、 Pathological 、 Matrix metalloproteinase 、 Fibrosis 、 Transforming growth factor 、 Chemistry
摘要: Matrix metalloproteinases (MMPs) and TGF-β play a crucial role not only in regulating growth development, tissue maintenance, wound healing, but also pathological processes like fibrosis tumor progression, metastases. Expression activation of MMPs are tightly regulated. Interestingly, involved proteolytic TGF-β, regulates expression levels MMPs. Here, we discuss the functional interactions normal tissues.
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