Occurrence of the adenylate cyclase “G Protein” in membranes of Dictyosteliumdiscoideum
作者： Ben H. Leichtling , D.S. Coffman , Eric S. Yaeger , H.V. Rickenberg , W. al-Jumaliy
DOI: 10.1016/S0006-291X(81)80137-4
关键词: Cell biology 、 Cholera toxin 、 Membrane 、 NAD+ kinase 、 Adenylate kinase 、 G protein 、 Biochemistry 、 Substrate (chemistry) 、 Cyclase 、 Dictyostelium discoideum 、 Biology 、 Biophysics 、 Molecular biology
摘要: Summary The occurrence of a membranal GTP-binding protein in Dictyostelium discoideum is described. found the membranes both vegetative and developing amoebae, has molecular weight approximately 42,000 serves as substrate for NAD + -dependent ADP-ribosylation, catalyzed by cholera toxin. resembles regulatory factor (“G protein”) vertebrate adenylate cyclase may play an analogous role D. .
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