作者: Eduard Batlle , Hans Clevers
DOI: 10.1038/NM.4409
关键词: Epithelial–mesenchymal transition 、 Biology 、 Tumor microenvironment 、 Cell Plasticity 、 Cancer stem cell 、 Neuroscience 、 Cell Self Renewal 、 Tumor growth 、 Stem cell 、 Adult stem cell
摘要: The cancer stem cell (CSC) concept was proposed four decades ago, and states that tumor growth, analogous to the renewal of healthy tissues, is fueled by small numbers of dedicated …