Xylocoside G reduces amyloid-β induced neurotoxicity by inhibiting NF-κB signaling pathway in neuronal cells

作者: Yan Yu , Liang Zhou , Miao Sun , Ting Zhou , Kaiyin Zhong

DOI: 10.3233/JAD-2012-110779

关键词: Viability assayCell biologyNeuroinflammationNeuroprotectionTumor necrosis factor alphaSignal transductionChemistryMAPK/ERK pathwayp38 mitogen-activated protein kinasesNeurotoxicity

摘要: Amyloid-ß (Aß) peptide, which can invoke a cascade of inflammatory responses, is considered to play a causal role in the development and progress of Alzheimer’s disease (AD). …

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