E-Cadherin, CD44 and CD44v6 in Squamous Intraepithelial Lesions and Invasive Carcinomas of the Uterine Cervix: An Immunohistochemical Study

作者: C. Faleiro-Rodrigues , C. Lopes

DOI: 10.1159/000081729

关键词: Gene isoformEpitheliumImmunohistochemistryKoilocyteUterine cervixCD44Cell adhesion moleculeMedicinePathologyCadherin

摘要: Objective: To evaluate the immunoexpression pattern of E-cadherin, CD44std and variant isoform v6 in normal squamous epithelium, low high intraepithelial lesions (S

参考文章(41)
Ruth M. Henderson, Cell-to-Cell Contacts Springer, Boston, MA. pp. 47- 77 ,(1975) , 10.1007/978-1-4684-2751-6_2
H Valentin, S Huet, A M Prieur, B Caillou, A Bernard, H Groux, CD44 contributes to T cell activation. Journal of Immunology. ,vol. 143, pp. 798- 801 ,(1989)
Setsuo Hirohashi, Akira Nagafuchi, Masatoshi Takeichi, Shin Fujita, Shoichiro Tsukita, Masahiro Gotoh, Yutaka Shimoyama, Cadherin Dysfunction in a Human Cancer Cell Line: Possible Involvement of Loss of α-Catenin Expression in Reduced Cell-Cell Adhesiveness Cancer Research. ,vol. 52, pp. 5770- 5774 ,(1992)
Magnus Von Knebel Doeberitz, Peter Melsheimer, Stefan M. Woerner, Margot Zöller, Achim Schneider, Jeannine Lacroix, Mehdi Givehchian, Serban Costa, Matthias Dürst, Expression of CD44 splice variants in normal, dysplastic, and neoplastic cervical epithelium. Clinical Cancer Research. ,vol. 1, pp. 1125- 1132 ,(1995)
Helmut Ponta, Wolfgang Rudy, Margot Zöller, Peter Herrlich, Martin Hofmann, Ursula Günthert, Cornelia Tölg, CD44 splice variants confer metastatic behavior in rats: homologous sequences are expressed in human tumor cell lines. Cancer Research. ,vol. 51, pp. 5292- 5297 ,(1991)
J Kawanishi, J Kato, K Sasaki, S Fujii, N Watanabe, Y Niitsu, Loss of E-cadherin-dependent cell-cell adhesion due to mutation of the beta-catenin gene in a human cancer cell line, HSC-39. Molecular and Cellular Biology. ,vol. 15, pp. 1175- 1181 ,(1995) , 10.1128/MCB.15.3.1175
Andrew H. Huber, Daniel B. Stewart, Douglas V. Laurents, W. James Nelson, William I. Weis, The Cadherin Cytoplasmic Domain Is Unstructured in the Absence of β-Catenin Journal of Biological Chemistry. ,vol. 276, pp. 12301- 12309 ,(2001) , 10.1074/JBC.M010377200
C.H. Damsky, Cell-to-cell contact Current Opinion in Cell Biology. ,vol. 1, pp. 881- 883 ,(1989) , 10.1016/0955-0674(89)90053-7
Ursula Günthert, Martin Hofmann, Wolfgang Rudy, Sonja Reber, Margot Zöller, Irmgard Hauβmann, Siegfried Matzku, Achim Wenzel, Helmut Ponta, Peter Herrlich, A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells Cell. ,vol. 65, pp. 13- 24 ,(1991) , 10.1016/0092-8674(91)90403-L