Active organization of membrane constituents in living cells.

摘要: A search for organizing principles underlying molecular patterning at the cell surface and its regulation over different scales is necessary. This important understanding how builds membrane bound organelles that emanate from it interacts with physical chemical milieu. requires a broad framework to rationalize mass of accumulated data about spatial localization dynamics constituents, their environment. Lateral heterogeneities in organization components living appear be hallmark addresses sorting signaling functions. Here we explore two classes mechanisms segregation plasma membrane. We suggest viewing as passive, thermally equilibrated system unlikely provide an adequate understand component vivo. Instead cells behaves active composite.