Tumor necrosis factor primes hepatocytes for DNA replication in the rat

作者: Eric M. Webber , Jordi Bruix , Robert H. Pierce , Nelson Fausto

DOI: 10.1002/HEP.510280509

关键词: Liver regenerationHepatocyte growth factorTumor necrosis factor alphaInternal medicineLiver cytologyGrowth factorSTAT3HepatocyteBiologyEndocrinologyTransforming growth factor

摘要: … that TNF may perform a priming function to initiate the DNA replication of hepatocytes in vivo. To … We show that TNF acts as a primer to sensitize hepatocytes to the proliferative effects of …

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