A 3D Interconnected Microchannel Network Formed in Gelatin by Sacrificial Shellac Microfibers
作者： Leon M. Bellan , Matthew Pearsall , Donald M. Cropek , Robert Langer
关键词: Solubility 、 Composite material 、 Microfiber 、 Dissolution 、 Aqueous solution 、 Materials science 、 Microfluidics 、 Shellac 、 Microchannel 、 Gelatin
摘要: 3D microfluidic networks are fabricated in a gelatin hydrogel using sacrificial melt-spun microfibers made from material with pH-dependent solubility. The fibers, after being embedded within the gel, can be removed by changing gel pH to induce dissolution. This process is performed an entirely aqueous environment, avoiding extreme temperatures, low pressures, and toxic organic solvents.
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