3D reconstruction of histological sections: Application to mammary gland tissue
作者： Ignacio Arganda‐Carreras , Rodrigo Fernández‐González , Arrate Muñoz‐Barrutia , Carlos Ortiz‐De‐Solorzano , None
DOI: 10.1002/JEMT.20829
关键词:
摘要: In this article, we present a novel method for the automatic 3D reconstruction of thick tissue blocks from 2D histological sections. The algorithm completes high-content (multiscale, multifeature) imaging system simultaneous morphological and molecular analysis samples. This computer-based integrates image acquisition, annotation, registration, three-dimensional reconstruction. We an experimental validation tool using both synthetic real data. particular, entire mouse mammary gland demonstrate integration high-resolution
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