Immunological Memory and Infection
作者： Rafi Ahmed , J. Gibson Lanier , Eric Pamer
DOI: 10.1128/9781555817978.CH13
关键词: Acquired immune system 、 Immunological memory 、 Antibody 、 Antibody production 、 Anatomic Location 、 Vaccination 、 Rapid rise 、 Immunology 、 Cell type 、 Biology
摘要: This chapter focuses on the principles of immune memory. It is divided into four parts: (i) a historical perspective vaccination, (ii) an overview protective immunity to microbes, (iii) discussion current models memory T- and B-cell differentiation, (iv) mechanisms involved in maintaining immunological Microbial infections usually induce both long-term The kinetics anatomic location antibody production after acute viral infection are shown. In summary, compartment consists B cells plasma cells: two distinct cell types with different locations very functions. rapid rise levels reinfection result differentiation new antibody-secreting cells. Since preexisting provides first line defense against by microbial pathogens, importance cannot be overstated. fact, it could argued that may single most important type infections. conclusion, this attempt has been made give infection. remains one exciting areas immunology infectious diseases, there many challenges ahead.
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