DNA Pooling as a Tool for Case-Control Association Studies of Complex Traits
作者： Terri M. King , Ahn Chul , Kang Seung-Ho , Lee Kyu-Snag
DOI:
关键词: Genetics 、 Genotyping 、 Case control association 、 Biology 、 Dna pooling 、 Genetic association 、 Disease gene
摘要: Case-control studies are widely used for disease gene mapping using individual genotyping data. However, analyses of large samples often impractical due to the expense genotyping. The use DNA pooling can significantly reduce number reactions required; hence reducing cost large-scale case-control association studies. Here, we discuss design and analysis genetic
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