Lung Cancer in Women: A Single Institution Experience with 50 Patients

作者: Nalan Akgul Babacan , Birsen Yucel , Saadettin Kilickap , Mehmet Metin Seker , Turgut Kacan

DOI: 10.7314/APJCP.2014.15.1.151

关键词: Small-cell carcinomaLung cancerIncidence (epidemiology)OncologyAdenocarcinomaInternal medicineECOG Performance StatusAnemiaUnivariate analysisStage (cooking)Medicine

摘要: Background: Lung cancer is the most common cause of cancer-related death worldwide. The incidence lung aproximately 7-8 thousand percent in Turkish women. In this study, we aimed to evaluate clinical, pathological properties and survival data female patients with who were treated our center. Materials Methods: From 2007 2012, 50 women enrolled. Patient evaluated retrospectively. Results: median age was 61 (40-81). Forty (80%) diagnosed non small cell (NSCLC), 10 (20%) carcinoma (SCC). Twelve (24%) smokers 13 16 non-smokers had a history exposure asbestos. histologic subtype adenocarcinoma (46%) accounted for 71% initial Eastern Cooperative Oncology Group (ECOG) performance score 1 (24 patients, 48%) stage IV (25 50%) study group. During 15 months (1-96 months) follow up period: year overall (OS) 68%, 2 36% time 19 months. According univariate analysis, poor ECOG status, advanced stage, anemia weight loss at diagnosis negative prognostic factors. However, sub-type positive factor. Conclusions: NSCLC sub-type, score, factors cancer.

参考文章(42)
R C Brownson, M C Alavanja, E T Hock, T S Loy, Passive smoking and lung cancer in nonsmoking women. American Journal of Public Health. ,vol. 82, pp. 1525- 1530 ,(1992) , 10.2105/AJPH.82.11.1525
C. Bosetti, P. Bertuccio, M. Malvezzi, F. Levi, L. Chatenoud, E. Negri, C. La Vecchia, Cancer mortality in Europe, 2005–2009, and an overview of trends since 1980 Annals of Oncology. ,vol. 24, pp. 2657- 2671 ,(2013) , 10.1093/ANNONC/MDT301
Ahmedin Jemal, Freddie Bray, Melissa M. Center, Jacques Ferlay, Elizabeth Ward, David Forman, Global cancer statistics CA: A Cancer Journal for Clinicians. ,vol. 61, pp. 69- 90 ,(1999) , 10.3322/CAAC.20107
Prognostic Factors for Survival in Patients With Inoperable Lung Cancer Journal of the National Cancer Institute. ,vol. 65, pp. 25- 32 ,(1980) , 10.1093/JNCI/65.1.25
S. Darby, D. Hill, R. Doll, Radon: A likely carcinogen at all exposures Annals of Oncology. ,vol. 12, pp. 1341- 1351 ,(2001) , 10.1023/A:1012518223463
Ahmedin Jemal, Melissa M. Center, Carol DeSantis, Elizabeth M. Ward, Global Patterns of Cancer Incidence and Mortality Rates and Trends Cancer Epidemiology, Biomarkers & Prevention. ,vol. 19, pp. 1893- 1907 ,(2010) , 10.1158/1055-9965.EPI-10-0437
Smoking and other risk factors for lung cancer in women. Journal of the National Cancer Institute. ,vol. 74, pp. 747- 751 ,(1985) , 10.1093/JNCI/74.4.747
Relin Yang, Michael C. Cheung, Felipe E. Pedroso, Margaret M. Byrne, Leonidas G. Koniaris, Teresa A. Zimmers, Obesity and weight loss at presentation of lung cancer are associated with opposite effects on survival Journal of Surgical Research. ,vol. 170, ,(2011) , 10.1016/J.JSS.2011.04.061