Identification of a new tadalafil analogue, dipropylaminopretadalafil, in a dietary supplement
作者： Yen-Chun Huang , Hui-Chun Lee , Yun-Lian Lin , Chia-Fen Tsai , Hwei-Fang Cheng
DOI: 10.1080/19440049.2016.1184530
关键词: High-performance liquid chromatography 、 Chromatography 、 Tadalafil 、 Dietary supplement 、 Column chromatography 、 Chemistry 、 Stereochemistry
摘要: A novel tadalafil analogue in a dietary supplement was found by drug-adulteration screening and isolated column chromatography HPLC. Based on extensive 1D- 2D-NMR mass spectral analyses, the structure of this new compound determined as 2-(N,N-dipropyl acetyl) 3-methyl 1-(benzo[d][1,3]dioxol-5-yl)-3,4-dihydro-1H-pyrido[3,4-b]indole-3-carboxylate - its common name is dipropylaminopretadalafil.
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