Increased population use of medications for male lower urinary tract symptoms/benign prostatic hyperplasia correlates with changes in indications for transurethral resection of the prostate.

作者: Johann P. Ingimarsson , Helgi J. Isaksson , Hermann P. Sigbjarnarson , Jens Gudmundsson , Gudmundur Geirsson

DOI: 10.3109/21681805.2013.825878

关键词: Transurethral resection of the prostateMale lower urinary tractBenign prostate hypertrophyPopulationHyperplasia5 Alpha-Reductase InhibitorLower urinary tract symptomsIncidence (epidemiology)UrologyMedicine

摘要: Abstract Objective. The aim of this study was to determine whether there are correlations between medication use for lower urinary tract symptoms/benign prostate hypertrophy (LUTS/BPH) and alteration in incidence indications transurethral resection the (TURP). Material methods. number TURP patients 1984 2008 Iceland obtained from hospital registries. defined daily doses (DDDs) 5-alpha-reductase inhibitors (5aRIs) alpha-blockers (ABs) sold Icelandic Medicines Control Agency. Charts all surgical BPH 1998 were retrospectively reviewed. main outcomes measures were: DDDs 5aRIs ABs, total numbers TURP, complications. Results. After introduction ABs 5aRIs, sales increased annually at a near linear rate. rates peaked 1992, then declined. In 2008, 81 3.4 1000 men over age 50 used LUTS/BPH medications or underwen...

参考文章(23)
Jason Izard, J. Curtis Nickel, Impact of medical therapy on transurethral resection of the prostate: two decades of change BJU International. ,vol. 108, pp. 89- 93 ,(2011) , 10.1111/J.1464-410X.2010.09737.X
Dena L. Walsh, Sam S. Chang, Dilemmas in the treatment of urothelial cancers of the prostate Urologic Oncology: Seminars and Original Investigations. ,vol. 27, pp. 352- 357 ,(2009) , 10.1016/J.UROLONC.2007.12.010
WILLIAM B. BAINE, WILLIAM YU, JAMES P. SUMME, KATHLEEN A. WEIS, EPIDEMIOLOGIC TRENDS IN THE EVALUATION AND TREATMENT OF LOWER URINARY TRACT SYMPTOMS IN ELDERLY MALE MEDICARE PATIENTS FROM 1991 TO 1995 The Journal of Urology. ,vol. 160, pp. 816- 820 ,(1998) , 10.1016/S0022-5347(01)62794-0
Paul Blomqvist, Anders Ekbom, Per Carlsson, Christer Ahlstrand, Jan-Erik Johansson, Benign prostatic hyperplasia in Sweden 1987 to 1994: changing patterns of treatment, changing patterns of costs. Urology. ,vol. 50, pp. 214- 220 ,(1997) , 10.1016/S0090-4295(97)00241-0
J Y Kang, G E Min, H Son, H T Kim, H-L Lee, National-wide data on the treatment of BPH in Korea Prostate Cancer and Prostatic Diseases. ,vol. 14, pp. 243- 247 ,(2011) , 10.1038/PCAN.2011.12
C.R. Chapple, R. Berges, F.F.H. Rutten, N.J.A. van Exel, M.A. Koopmanschap, J. McDonnell, Medical consumption and costs during a one-year follow-up of patients with LUTS suggestive of BPH in six european countries: report of the TRIUMPH study. European Urology. ,vol. 49, pp. 92- 102 ,(2006) , 10.1016/J.EURURO.2005.09.016
J.H. WASSON, T.A. BUBOLZ, G.L. LU-YAO, E. WALKER-CORKERY, C.S. HAMMOND, M.J. BARRY, , TRANSURETHRAL RESECTION OF THE PROSTATE AMONG MEDICARE BENEFICIARIES: 1984 TO 1997 The Journal of Urology. ,vol. 164, pp. 1212- 1215 ,(2000) , 10.1016/S0022-5347(05)67143-1