作者: Johann P. Ingimarsson , Helgi J. Isaksson , Hermann P. Sigbjarnarson , Jens Gudmundsson , Gudmundur Geirsson
DOI: 10.3109/21681805.2013.825878
关键词: Transurethral resection of the prostate 、 Male lower urinary tract 、 Benign prostate hypertrophy 、 Population 、 Hyperplasia 、 5 Alpha-Reductase Inhibitor 、 Lower urinary tract symptoms 、 Incidence (epidemiology) 、 Urology 、 Medicine
摘要: Abstract Objective. The aim of this study was to determine whether there are correlations between medication use for lower urinary tract symptoms/benign prostate hypertrophy (LUTS/BPH) and alteration in incidence indications transurethral resection the (TURP). Material methods. number TURP patients 1984 2008 Iceland obtained from hospital registries. defined daily doses (DDDs) 5-alpha-reductase inhibitors (5aRIs) alpha-blockers (ABs) sold Icelandic Medicines Control Agency. Charts all surgical BPH 1998 were retrospectively reviewed. main outcomes measures were: DDDs 5aRIs ABs, total numbers TURP, complications. Results. After introduction ABs 5aRIs, sales increased annually at a near linear rate. rates peaked 1992, then declined. In 2008, 81 3.4 1000 men over age 50 used LUTS/BPH medications or underwen...