Nuclear and chromatin lipids: metabolism in normal and γ-irradiated rats

作者: I.K Kolomiytseva , T.P Kulagina , L.N Markevich , V.I Archipov , L.V Slozhenikina

DOI: 10.1016/S1567-5394(02)00126-3

关键词: Lipid metabolismBiochemistryCell biologyBiologyMetabolismChromatinNeuronDose ratePicrotoxinSignal transductionNeocortex

摘要: Abstract The data on nuclear and chromatin lipid metabolism are reviewed. amount of neutral lipids phospholipids in nuclei rat thymus, liver neocortex neuron as well the thymus described. metabolic responses from to different doses dose rates γ-irradiation rats discussed. In most cases, distinct. Changes response suggested connect with signal transduction pathway regulation transcriptional replicative activity. influence β-carotene picrotoxin neuronal lipids, respectively, was analyzed. possible involvement traffic other agents is suggested.

参考文章(51)
I.K. Kolomiytseva, L.V. Slozhenikina, L.A. Fialkovskaya, T.P. Kulagina, L.N. Markevich, N.I. Potekhina, Nonmonotonous Changes in Metabolic Parameters of Tissues and Cells under Action of Ionizing Radiation on Animal. Journal of Biological Physics. ,vol. 25, pp. 325- 338 ,(1999) , 10.1023/A:1005147109299
I.K. Kolomiitseva, L.N. Markevich, Lipid composition of liver microsomes and mitochondria after acute and chronic {gamma}-irradiation of rats Biochemistry. ,vol. 59, pp. 767- 771 ,(1994)
Y A Hannun, C R Loomis, R M Bell, Activation of Protein Kinase C by Triton X-100 Mixed Micelles Containing Diacylglycerol and Phosphatidylserine* Journal of Biological Chemistry. ,vol. 260, pp. 10039- 10043 ,(1985) , 10.1016/S0021-9258(17)39208-6
Nadir M Maraldi, S. Santi, N. Zini, A. Ognibene, Riccardo Rizzoli, G. Mazzotti, Roberto Di Primio, R. Bareggi, V. Bertagnolo, Carla Pagliarini, Silvano Capitani, Decrease in nuclear phospholipids associated with DNA replication Journal of Cell Science. ,vol. 104, pp. 853- 859 ,(1993)
I.K. Kolomiytseva, E.G. Novoselova, T.P. Kulagina, A.M. Kuzin, The effect of ionizing radiation on lipid metabolism in lymphoid cells. International Journal of Radiation Biology. ,vol. 51, pp. 53- 58 ,(1987) , 10.1080/09553008714550491
Elisabetta Albi, MP Viola-Magni, CHOLINE BASE EXCHANGE ACTIVITY IN RAT HEPATOCYTE NUCLEI AND NUCLEAR MEMBRANES Cell Biology International. ,vol. 21, pp. 217- 221 ,(1997) , 10.1006/CBIR.1997.0133
Mechthild Regenass-Klotz, Hans-Jörg Heiniger, Specific binding of cholesterol to chromatin prepared from mouse spleen cells. Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire. ,vol. 62, pp. 94- 99 ,(1984) , 10.1139/O84-014
John P Incardona, Suzanne Eaton, Cholesterol in signal transduction. Current Opinion in Cell Biology. ,vol. 12, pp. 193- 203 ,(2000) , 10.1016/S0955-0674(99)00076-9
S.R. Umansky, Yu.I. Kovalev, V.I. Tokarskaya, Specific interaction of chromatin non-histone proteins with DNA. Biochimica et Biophysica Acta. ,vol. 383, pp. 242- 254 ,(1975) , 10.1016/0005-2787(75)90053-2