Lipids of nuclear fractions from neurons and glia of rat neocortex under conditions of artificial hypobiosis
作者： I. K. Kolomiytseva , L. N. Markevich , D. A. Ignat’ev , O. V. Bykova
DOI: 10.1134/S0006297910090063
关键词:
摘要: Lipid contents were studied in tissue and nuclei isolated from neurons glia of neocortex rats under conditions normothermia the state artificial hypobiosis caused by hypothermia-hypoxia-hypercapnia. Compared to tissue, both nuclear fractions fivefold impoverished phospholipids cholesterol strongly enriched with mono- diglycerides fatty acids. The contained similar amounts phospholipids, only cardiolipin content neuronal was lower than glial nuclei. led an increase cholesterol/phospholipids ratio (mol/mol) glia; sphingomyelin increased. increases suggest involvement lipid-dependent signaling systems functional response mammalian cells hypobiosis.
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